Endocrine Abstracts

Decorin is myokine expressed and released in response to muscle contractions. It induces growth and hypertrophy of skeletal muscles in different ways including myostatin inhibition. It is still not clear whether decorin takes part in development of muscle atrophy in endocrine pathologies.Objective: To evaluate decorin levels in patients with endogenous hypercortisolism and GH oversecretion.Materials and methods: Three groups were i...

Introduction: In previous studies, it was noted that increased serum growth hormone (GH) and insulin-like growth factor-1 (IGF-1) lead to the increased vertebral fractures risk in patients with acromegaly. This may be explained by the altered quality of bone rather than bone mineral density (BMD) loss. Trabecular bone score (TBS) is an easily available tool to obtain some surrogate information on bone microarchitecture from a routine DXA.Objective: To ev...